Effect of hepatocarcinogens on hepatocyte DNA synthesis and cortisone induction of tryptophan oxygenase.
نویسندگان
چکیده
hepatocyte DNA synthesis, inhibited tryptophan oxygenase induction, and stimulated AMP deaminase activity. Simul taneous administration of ethionine with thioacetamide inhibited DNA synthesis. AMP deaminase activity was not stimulated appreciably during liver regeneration, and the modest changes recorded could not be readily attributed to hepatocyte DNA synthesis or mitosis. The relationship between changes in cellularity in precancerous liver and stimulated AMP deaminase activity was discussed.
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ورودعنوان ژورنال:
- Cancer research
دوره 29 11 شماره
صفحات -
تاریخ انتشار 1969